human RPTOR shRNA silencing AAV

Cat. No: shAAV-212993

Availability: 4-5 weeks

Name: AAV-h-RPTOR-shRNA

This is an AAV expressing shRNA for silencing of Human RPTOR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RPTOR
Gene Name: regulatory associated protein of MTOR complex 1
Gene ID: 57521
Gene Synonyms: KOG1; Mip1
ORF Size: 4008 bp
RefSeq#: NM_020761
Gene Description: RPTOR encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.133044
HGNC ID: HGNC:30287