human KCNMB2 shRNA silencing AAV

Cat. No: shAAV-212761

Availability: 6-8 weeks

Name: AAV-h-KCNMB2-shRNA

This is an AAV expressing shRNA for silencing of Human KCNMB2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNMB2
Gene Name: potassium calcium-activated channel subfamily M regulatory beta subunit 2
Gene ID: 10242
ORF Size: 708 bp
RefSeq#: NM_005832
Gene Description: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene.
UniGene ID: Hs.478368
HGNC ID: HGNC:6286