human KCNIP4 shRNA silencing AAV

Cat. No: shAAV-212707

Availability: 6-8 weeks

Name: AAV-h-KCNIP4-shRNA

This is an AAV expressing shRNA for silencing of Human KCNIP4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNIP4
Gene Name: potassium voltage-gated channel interacting protein 4
Gene ID: 80333
Gene Synonyms: CALP; KCHIP4
ORF Size: 753 bp
RefSeq#: NM_025221
Gene Description: KCNIP4 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
UniGene ID: Hs.655705
HGNC ID: HGNC:30083