human KCNH7 shRNA silencing AAV

Cat. No: shAAV-212702

Availability: 6-8 weeks

Name: AAV-h-KCNH7-shRNA

This is an AAV expressing shRNA for silencing of Human KCNH7.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNH7
Gene Name: potassium voltage-gated channel subfamily H member 7
Gene ID: 90134
Gene Synonyms: ERG3; HERG3; Kv11.3
ORF Size: 2199 bp
RefSeq#: NM_033272
Gene Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
UniGene ID: Hs.657413
HGNC ID: HGNC:18863