human KCNE1 shRNA silencing AAV

Cat. No: shAAV-212683

Availability: 6-8 weeks

Name: AAV-h-KCNE1-shRNA

This is an AAV expressing shRNA for silencing of Human KCNE1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNE1
Gene Name: potassium voltage-gated channel subfamily E regulatory subunit 1
Gene ID: 3753
Gene Synonyms: ISK; JLNS; JLNS2; LQT2/5; LQT5; MinK
ORF Size: 390 bp
RefSeq#: NM_000219
Gene Description: The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
UniGene ID: Hs.121495
HGNC ID: HGNC:6240