human JMJD6 shRNA silencing AAV

Cat. No: shAAV-212584

Availability: 4-5 weeks

Name: AAV-h-JMJD6-shRNA

This is an AAV expressing shRNA for silencing of Human JMJD6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: JMJD6
Gene Name: arginine demethylase and lysine hydroxylase
Gene ID: 23210
Gene Synonyms: PSR; PTDSR; PTDSR1
ORF Size: 1212 bp
RefSeq#: NM_015167
Gene Description: JMJD6 encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.514505
HGNC ID: HGNC:19355