human JAM2 shRNA silencing AAV

Cat. No: shAAV-212576

Availability: 6-8 weeks

Name: AAV-h-JAM2-shRNA

This is an AAV expressing shRNA for silencing of Human JAM2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: JAM2
Gene Name: junctional adhesion molecule 2
Gene ID: 58494
Gene Synonyms: C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM
ORF Size: 897 bp
RefSeq#: NM_021219
Gene Description: JAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.517227
HGNC ID: HGNC:14686