human JAK3 shRNA silencing AAV

Cat. No: shAAV-212574

Availability: 4-5 weeks

Name: AAV-h-JAK3-shRNA

This is an AAV expressing shRNA for silencing of Human JAK3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: JAK3
Gene Name: Janus kinase 3
Gene ID: 3718
Gene Synonyms: JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
ORF Size: 1860 bp
RefSeq#: NM_000215
Gene Description: JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
UniGene ID: Hs.515247
HGNC ID: HGNC:6193