human JAK2 shRNA silencing AAV

Cat. No: shAAV-212573

Availability: 4-5 weeks

Name: AAV-h-JAK2-shRNA

This is an AAV expressing shRNA for silencing of Human JAK2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: JAK2
Gene Name: Janus kinase 2
Gene ID: 3717
Gene Synonyms: JTK10; THCYT3
ORF Size: 3390 bp
RefSeq#: NM_004972
Gene Description: JAK2 product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
UniGene ID: Hs.656213
HGNC ID: HGNC:6192