human ITSN2 shRNA silencing AAV

Cat. No: shAAV-212560

Availability: 4-5 weeks

Name: AAV-h-ITSN2-shRNA

This is an AAV expressing shRNA for silencing of Human ITSN2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ITSN2
Gene Name: intersectin 2
Gene ID: 50618
Gene Synonyms: PRO2015; SH3D1B; SH3P18; SWA; SWAP
ORF Size: 5010 bp
RefSeq#: NM_019595
Gene Description: ITSN2 encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined.
UniGene ID: Hs.432562
HGNC ID: HGNC:6184