human ITPKA shRNA silencing AAV

Cat. No: shAAV-212546

Availability: 6-8 weeks

Name: AAV-h-ITPKA-shRNA

This is an AAV expressing shRNA for silencing of Human ITPKA.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ITPKA
Gene Name: inositol-trisphosphate 3-kinase A
Gene ID: 3706
Gene Synonyms: IP3-3KA; IP3KA
ORF Size: 1386 bp
RefSeq#: NM_002220
Gene Description: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
UniGene ID: Hs.2722
HGNC ID: HGNC:6178