human IRF1 shRNA silencing AAV

Cat. No: shAAV-212399

Availability: 4-5 weeks

Name: AAV-h-IRF1-shRNA

This is an AAV expressing shRNA for silencing of Human IRF1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IRF1
Gene Name: interferon regulatory factor 1
Gene ID: 3659
Gene Synonyms: IRF-1; MAR
ORF Size: 978 bp
RefSeq#: NM_002198
Gene Description: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
UniGene ID: Hs.436061
HGNC ID: HGNC:6116