human IQGAP1 shRNA silencing AAV

Cat. No: shAAV-212379

Availability: 4-5 weeks

Name: AAV-h-IQGAP1-shRNA

This is an AAV expressing shRNA for silencing of Human IQGAP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IQGAP1
Gene Name: IQ motif containing GTPase activating protein 1
Gene ID: 8826
Gene Synonyms: HUMORFA01; p195; SAR1
ORF Size: 4974 bp
RefSeq#: NM_003870
Gene Description: IQGAP1 encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
UniGene ID: Hs.430551
HGNC ID: HGNC:6110