human IL1RAPL1 shRNA silencing AAV

Cat. No: shAAV-212112

Availability: 6-8 weeks

Name: AAV-h-IL1RAPL1-shRNA

This is an AAV expressing shRNA for silencing of Human IL1RAPL1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IL1RAPL1
Gene Name: interleukin 1 receptor accessory protein like 1
Gene ID: 11141
Gene Synonyms: IL1R8; IL1RAPL; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2
ORF Size: 2091 bp
RefSeq#: NM_014271
Gene Description: IL1RAPL1 is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.
UniGene ID: Hs.658912
HGNC ID: HGNC:5996