human IKBKB shRNA silencing AAV

Cat. No: shAAV-212008

Availability: 4-5 weeks

Name: AAV-h-IKBKB-shRNA

This is an AAV expressing shRNA for silencing of Human IKBKB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IKBKB
Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene ID: 3551
Gene Synonyms: FLJ33771; FLJ36218; FLJ38368; FLJ40509; IKK-beta; IKK2; IKKB; MGC131801; NFKBIKB;
ORF Size: 1263 bp
RefSeq#: NM_001556
Gene Description: IKBKB phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
UniGene ID: Hs.597664
HGNC ID: HGNC:5960