human IHH shRNA silencing AAV

Cat. No: shAAV-212003

Availability: 6-8 weeks

Name: AAV-h-IHH-shRNA

This is an AAV expressing shRNA for silencing of Human IHH.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IHH
Gene Name: indian hedgehog
Gene ID: 3549
Gene Synonyms: BDA1; HHG2
ORF Size: 1236 bp
RefSeq#: NM_002181
Gene Description: IHH encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
UniGene ID: Hs.654504
HGNC ID: HGNC:5956