human IFNGR2 shRNA silencing AAV

Cat. No: shAAV-211878

Availability: 4-5 weeks

Name: AAV-h-IFNGR2-shRNA

This is an AAV expressing shRNA for silencing of Human IFNGR2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IFNGR2
Gene Name: interferon gamma receptor 2 (interferon gamma transducer 1)
Gene ID: 3460
Gene Synonyms: AF-1; IFGR2; IFNGT1; IMD28
ORF Size: 1014 bp
RefSeq#: NM_005534
Gene Description: IFNGR2 (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
UniGene ID: Hs.634632
HGNC ID: HGNC:5440