human HTRA1 shRNA silencing AAV

Cat. No: shAAV-211713

Availability: 4-5 weeks

Name: AAV-h-HTRA1-shRNA

This is an AAV expressing shRNA for silencing of Human HTRA1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HTRA1
Gene Name: HtrA serine peptidase 1
Gene ID: 5654
Gene Synonyms: ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
ORF Size: 1443 bp
RefSeq#: NM_002775
Gene Description: HTRA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
UniGene ID: Hs.501280
HGNC ID: HGNC:9476