human HTR3A shRNA silencing AAV

Cat. No: shAAV-211696

Availability: 6-8 weeks

Name: AAV-h-HTR3A-shRNA

This is an AAV expressing shRNA for silencing of Human HTR3A.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HTR3A
Gene Name: 5-hydroxytryptamine receptor 3A
Gene ID: 3359
Gene Synonyms: 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3
ORF Size: 1437 bp
RefSeq#: NM_000869
Gene Description: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniGene ID: Hs.413899
HGNC ID: HGNC:5297