human HSH2D shRNA silencing AAV

Cat. No: shAAV-211611

Availability: 6-8 weeks

Name: AAV-h-HSH2D-shRNA

This is an AAV expressing shRNA for silencing of Human HSH2D.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HSH2D
Gene Name: hematopoietic SH2 domain containing
Gene ID: 84941
Gene Synonyms: ALX; HSH2
ORF Size: 1059 bp
RefSeq#: NM_032855
Gene Description: T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 (PubMed 12960172)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.631617
HGNC ID: HGNC:24920