human HSF4 shRNA silencing AAV

Cat. No: shAAV-211599

Availability: 6-8 weeks

Name: AAV-h-HSF4-shRNA

This is an AAV expressing shRNA for silencing of Human HSF4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HSF4
Gene Name: heat shock transcription factor 4
Gene ID: 3299
Gene Synonyms: CTM; CTRCT5
ORF Size: 1386 bp
RefSeq#: NM_001538
Gene Description: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
UniGene ID: Hs.715679
HGNC ID: HGNC:5227