human HSD17B6 shRNA silencing AAV

Cat. No: shAAV-211579

Availability: 4-5 weeks

Name: AAV-h-HSD17B6-shRNA

This is an AAV expressing shRNA for silencing of Human HSD17B6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HSD17B6
Gene Name: hydroxysteroid 17-beta dehydrogenase 6
Gene ID: 8630
Gene Synonyms: HSE; RODH; SDR9C6
ORF Size: 954 bp
RefSeq#: NM_003725
Gene Description: HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.
UniGene ID: Hs.524513
HGNC ID: HGNC:23316