human HS3ST1 shRNA silencing AAV

Cat. No: shAAV-211536

Availability: 4-5 weeks

Name: AAV-h-HS3ST1-shRNA

This is an AAV expressing shRNA for silencing of Human HS3ST1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HS3ST1
Gene Name: heparan sulfate-glucosamine 3-sulfotransferase 1
Gene ID: 9957
Gene Synonyms: 3OST; 3OST1
ORF Size: 924 bp
RefSeq#: NM_005114
Gene Description: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein.
UniGene ID: Hs.605349
HGNC ID: HGNC:5194