human HOXB8 shRNA silencing AAV

Cat. No: shAAV-211460

Availability: 4-5 weeks

Name: AAV-h-HOXB8-shRNA

This is an AAV expressing shRNA for silencing of Human HOXB8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HOXB8
Gene Name: homeobox B8
Gene ID: 3218
Gene Synonyms: Hox-2.4; HOX2; HOX2D
ORF Size: 729 bp
RefSeq#: NM_024016
Gene Description: HOXB8 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
UniGene ID: Hs.514292
HGNC ID: HGNC:5119