human HOPX shRNA silencing AAV

Cat. No: shAAV-211427

Availability: 4-5 weeks

Name: AAV-h-HOPX-shRNA

This is an AAV expressing shRNA for silencing of Human HOPX.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HOPX
Gene Name: HOP homeobox
Gene ID: 84525
Gene Synonyms: CAMEO; HOD; HOP; LAGY; NECC1; OB1; SMAP31; TOTO
ORF Size: 222 bp
RefSeq#: NM_032495
Gene Description: HOPX is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene.
UniGene ID: Hs.654864
HGNC ID: HGNC:24961