human HNF1A shRNA silencing AAV

Cat. No: shAAV-211324

Availability: 6-8 weeks

Name: AAV-h-HNF1A-shRNA

This is an AAV expressing shRNA for silencing of Human HNF1A.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HNF1A
Gene Name: HNF1 homeobox A
Gene ID: 6927
Gene Synonyms: HNF-1A; HNF1; IDDM20; LFB1; MODY3; TCF-1; TCF1
ORF Size: 1896 bp
RefSeq#: NM_000545
Gene Description: HNF1A is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
UniGene ID: Hs.654455
HGNC ID: HGNC:11621