human HMOX2 shRNA silencing AAV

Cat. No: shAAV-211315

Availability: 4-5 weeks

Name: AAV-h-HMOX2-shRNA

This is an AAV expressing shRNA for silencing of Human HMOX2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HMOX2
Gene Name: heme oxygenase 2
Gene ID: 3163
Gene Synonyms: HO-2
ORF Size: 951 bp
RefSeq#: NM_002134
Gene Description: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
UniGene ID: Hs.284279
HGNC ID: HGNC:5014