human HMGB2 shRNA silencing AAV

Cat. No: shAAV-211276

Availability: 4-5 weeks

Name: AAV-h-HMGB2-shRNA

This is an AAV expressing shRNA for silencing of Human HMGB2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HMGB2
Gene Name: high mobility group box 2
Gene ID: 3148
Gene Synonyms: HMG2
ORF Size: 630 bp
RefSeq#: NM_002129
Gene Description: HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
UniGene ID: Hs.434953
HGNC ID: HGNC:5000