human HIST1H4B shRNA silencing AAV

Cat. No: shAAV-211148

Availability: 4-5 weeks

Name: AAV-h-HIST1H4B-shRNA

This is an AAV expressing shRNA for silencing of Human HIST1H4B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HIST1H4B
Gene Name: histone cluster 1 H4 family member b
Gene ID: 8366
Gene Synonyms: H4/I; H4FI
ORF Size: 312 bp
RefSeq#: NM_003544
Gene Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
UniGene ID: Hs.143080
HGNC ID: HGNC:4789