human HIST1H2AA shRNA silencing AAV

Cat. No: shAAV-211065

Availability: 6-8 weeks

Name: AAV-h-HIST1H2AA-shRNA

This is an AAV expressing shRNA for silencing of Human HIST1H2AA.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HIST1H2AA
Gene Name: histone cluster 1 H2A family member a
Gene ID: 221613
Gene Synonyms: bA317E16.2; H2AA; H2AFR; TH2A
ORF Size: 396 bp
RefSeq#: NM_170745
Gene Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element.
UniGene ID: Hs.406739
HGNC ID: HGNC:18729