human HERV-FRD shRNA silencing AAV

Cat. No: shAAV-210962

Availability: 6-8 weeks

Name: AAV-h-HERV-FRD-shRNA

This is an AAV expressing shRNA for silencing of Human ERVFRD-1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ERVFRD-1
Gene Name: endogenous retrovirus group FRD member 1
Gene ID: 405754
Gene Synonyms: envFRD; ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; UNQ6191
ORF Size: 1617 bp
RefSeq#: NM_207582
Gene Description: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
UniGene ID: Hs.631996
HGNC ID: HGNC:33823