human HDAC4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-210889
Availability:
Immediate
Name:
AAV-h-HDAC4-shRNA
This is an AAV expressing shRNA for silencing of Human HDAC4.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HDAC4
- Gene Name
- histone deacetylase 4
- Gene ID
- 9759
- Gene Synonyms
- AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA
- ORF Size
- 2919 bp
- RefSeq#
- NM_006037
- Gene Description
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
- UniGene ID
- Hs.688314
- HGNC ID
- HGNC:14063
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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