human HDAC1 shRNA silencing AAV

Cat. No: shAAV-210883

Availability: 4-5 weeks

Name: AAV-h-HDAC1-shRNA

This is an AAV expressing shRNA for silencing of Human HDAC1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HDAC1
Gene Name: histone deacetylase 1
Gene ID: 3065
Gene Synonyms: GON-10; HD1; RPD3; RPD3L1
ORF Size: 1449 bp
RefSeq#: NM_004964
Gene Description: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
UniGene ID: Hs.88556
HGNC ID: HGNC:4852