human HAND1 shRNA silencing AAV

Cat. No: shAAV-210773

Availability: 4-5 weeks

Name: AAV-h-HAND1-shRNA

This is an AAV expressing shRNA for silencing of Human HAND1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HAND1
Gene Name: heart and neural crest derivatives expressed 1
Gene ID: 9421
Gene Synonyms: bHLHa27; eHand; Hxt; Thing1
ORF Size: 648 bp
RefSeq#: NM_004821
Gene Description: HAND1 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
UniGene ID: Hs.152531
HGNC ID: HGNC:4807