human GYPC shRNA silencing AAV

Cat. No: shAAV-210708

Availability: 6-8 weeks

Name: AAV-h-GYPC-shRNA

This is an AAV expressing shRNA for silencing of Human GYPC.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GYPC
Gene Name: glycophorin C (Gerbich blood group)
Gene ID: 2995
Gene Synonyms: CD236; CD236R; GE; GPC; GPD; GYPD; PAS-2; PAS-2'
ORF Size: 387 bp
RefSeq#: NM_002101
Gene Description: Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.59138
HGNC ID: HGNC:4704