human GOT2 shRNA silencing AAV

Cat. No: shAAV-210187

Availability: 4-5 weeks

Name: AAV-h-GOT2-shRNA

This is an AAV expressing shRNA for silencing of Human GOT2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GOT2
Gene Name: glutamic-oxaloacetic transaminase 2
Gene ID: 2806
Gene Synonyms: KAT4; KATIV; KYAT4; mitAAT
ORF Size: 1293 bp
RefSeq#: NM_002080
Gene Description: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
UniGene ID: Hs.599470
HGNC ID: HGNC:4433