human GLUL shRNA silencing AAV

Cat. No: shAAV-210021

Availability: 4-5 weeks

Name: AAV-h-GLUL-shRNA

This is an AAV expressing shRNA for silencing of Human GLUL.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GLUL
Gene Name: glutamate-ammonia ligase
Gene ID: 2752
Gene Synonyms: GLNS; GS; PIG43; PIG59
ORF Size: 1122 bp
RefSeq#: NM_002065
Gene Description: GLUL belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.518525
HGNC ID: HGNC:4341