human GLRX5 shRNA silencing AAV

Cat. No: shAAV-210000

Availability: 4-5 weeks

Name: AAV-h-GLRX5-shRNA

This is an AAV expressing shRNA for silencing of Human GLRX5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GLRX5
Gene Name: glutaredoxin 5
Gene ID: 51218
Gene Synonyms: C14orf87; FLB4739; GRX5; PR01238; PRO1238; PRSA; SIDBA3; SPAHGC
ORF Size: 474 bp
RefSeq#: NM_016417
Gene Description: GLRX5 encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia.
UniGene ID: Hs.532683
HGNC ID: HGNC:20134