human GLIPR1 shRNA silencing AAV

Cat. No: shAAV-209970

Availability: 4-5 weeks

Name: AAV-h-GLIPR1-shRNA

This is an AAV expressing shRNA for silencing of Human GLIPR1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GLIPR1
Gene Name: GLI pathogenesis related 1
Gene ID: 11010
Gene Synonyms: CRISP7; GLIPR; RTVP1
ORF Size: 801 bp
RefSeq#: NM_006851
Gene Description: GLIPR1 encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. GLIPR1 is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
UniGene ID: Hs.205558
HGNC ID: HGNC:17001