human GIP shRNA silencing AAV

Cat. No: shAAV-209895

Availability: 6-8 weeks

Name: AAV-h-GIP-shRNA

This is an AAV expressing shRNA for silencing of Human GIP.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GIP
Gene Name: gastric inhibitory polypeptide
Gene ID: 2695
ORF Size: 462 bp
RefSeq#: NM_004123
Gene Description: GIP encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. GIP stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
UniGene ID: Hs.1454
HGNC ID: HGNC:4270