human GEMIN4 shRNA silencing AAV

Cat. No: shAAV-209805

Availability: 4-5 weeks

Name: AAV-h-GEMIN4-shRNA

This is an AAV expressing shRNA for silencing of Human GEMIN4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GEMIN4
Gene Name: gem nuclear organelle associated protein 4
Gene ID: 50628
Gene Synonyms: HC56; HCAP1; HHRF-1; p97
ORF Size: 3177 bp
RefSeq#: NM_015721
Gene Description: The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
UniGene ID: Hs.499620
HGNC ID: HGNC:15717