human GDF2 shRNA silencing AAV

Cat. No: shAAV-209776

Availability: 6-8 weeks

Name: AAV-h-GDF2-shRNA

This is an AAV expressing shRNA for silencing of Human GDF2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GDF2
Gene Name: growth differentiation factor 2
Gene ID: 2658
Gene Synonyms: BMP-9; BMP9; HHT5
ORF Size: 1290 bp
RefSeq#: NM_016204
Gene Description: GDF2 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.
UniGene ID: Hs.279463
HGNC ID: HGNC:4217