human GDF10 shRNA silencing AAV

Cat. No: shAAV-209773

Availability: 6-8 weeks

Name: AAV-h-GDF10-shRNA

This is an AAV expressing shRNA for silencing of Human GDF10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GDF10
Gene Name: growth differentiation factor 10
Gene ID: 2662
Gene Synonyms: BIP; BMP-3b; BMP3B
ORF Size: 867 bp
RefSeq#: NM_004962
Gene Description: GDF10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.
UniGene ID: Hs.2171
HGNC ID: HGNC:4215