human GBF1 shRNA silencing AAV

Cat. No: shAAV-209708

Availability: 4-5 weeks

Name: AAV-h-GBF1-shRNA

This is an AAV expressing shRNA for silencing of Human GBF1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GBF1
Gene Name: golgi brefeldin A resistant guanine nucleotide exchange factor 1
Gene ID: 8729
Gene Synonyms: ARF1GEF
ORF Size: 5568 bp
RefSeq#: NM_004193
Gene Description: GBF1 encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.
UniGene ID: Hs.290243
HGNC ID: HGNC:4181