human GABRA6 shRNA silencing AAV

Cat. No: shAAV-209512

Availability: 6-8 weeks

Name: AAV-h-GABRA6-shRNA

This is an AAV expressing shRNA for silencing of Human GABRA6.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GABRA6
Gene Name: gamma-aminobutyric acid type A receptor alpha6 subunit
Gene ID: 2559
ORF Size: 1362 bp
RefSeq#: NM_000811
Gene Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
UniGene ID: Hs.90791
HGNC ID: HGNC:4080