human G6PC3 shRNA silencing AAV

Cat. No: shAAV-209482

Availability: 4-5 weeks

Name: AAV-h-G6PC3-shRNA

This is an AAV expressing shRNA for silencing of Human G6PC3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: G6PC3
Gene Name: glucose-6-phosphatase catalytic subunit 3
Gene ID: 92579
Gene Synonyms: SCN4; UGRP
ORF Size: 1041 bp
RefSeq#: NM_138387
Gene Description: G6PC3 encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.
UniGene ID: Hs.294005
HGNC ID: HGNC:24861