human G6PC2 shRNA silencing AAV

Cat. No: shAAV-209480

Availability: 6-8 weeks

Name: AAV-h-G6PC2-shRNA

This is an AAV expressing shRNA for silencing of Human G6PC2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: G6PC2
Gene Name: glucose-6-phosphatase catalytic subunit 2
Gene ID: 57818
Gene Synonyms: IGRP
ORF Size: 1068 bp
RefSeq#: NM_021176
Gene Description: G6PC2 encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.
UniGene ID: Hs.283963
HGNC ID: HGNC:28906