human FZD10 shRNA silencing AAV

Cat. No: shAAV-209457

Availability: 6-8 weeks

Name: AAV-h-FZD10-shRNA

This is an AAV expressing shRNA for silencing of Human FZD10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FZD10
Gene Name: frizzled class receptor 10
Gene ID: 11211
Gene Synonyms: CD350; FZ-10; Fz10; FzE7; hFz10
ORF Size: 1746 bp
RefSeq#: NM_007197
Gene Description: FZD10 is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
UniGene ID: Hs.31664
HGNC ID: HGNC:4039