human FYCO1 shRNA silencing AAV

Cat. No: shAAV-209451

Availability: 6-8 weeks

Name: AAV-h-FYCO1-shRNA

This is an AAV expressing shRNA for silencing of Human FYCO1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FYCO1
Gene Name: FYVE and coiled-coil domain containing 1
Gene ID: 79443
Gene Synonyms: CATC2; CTRCT18; RUFY3; ZFYVE7
ORF Size: 4437 bp
RefSeq#: NM_024513
Gene Description: FYCO1 encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
UniGene ID: Hs.714847
HGNC ID: HGNC:14673