human FOLR3 shRNA silencing AAV

Cat. No: shAAV-209220

Availability: 6-8 weeks

Name: AAV-h-FOLR3-shRNA

This is an AAV expressing shRNA for silencing of Human FOLR3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FOLR3
Gene Name: folate receptor 3
Gene ID: 2352
Gene Synonyms: FR-G; FR-gamma; gamma-hFR
ORF Size: 738 bp
RefSeq#: NM_000804
Gene Description: FOLR3 encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR3 includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively.
UniGene ID: Hs.352
HGNC ID: HGNC:3795